I’m currently writing a small literature review on tgf-b and SMAD signalling in cancer for uni rn
And I’m really confused why this one paper’s talking about how miR-520h induces the tgf-b/smad7 pathway but also binds to and suppresses smad7
Like why on earth is it activating the tgf-b/smad7 pathway, a pathway that stops stuff like the epithelial mesenchynal transition, if it’s just going to bind to smad7 anyway???
Worst thing is, I can’t find any other papers on why this actually happens
I swear I’m just dumb at times ;-;
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